Prinzmetals variant angina, chronic stable angina
Adolescent, adult: 30 mg PO qid ac and hs. Increase to max of 360 mg/day in 3-4 divided doses prn. Or, 120-180 mg (extended-release) PO once qd. Adjust dose over 7-14 day prn as tol to max of 480 mg/day.
Hypertension
Adolescent, adult: 60-120 mg PO bid (surt-rel) adjust to max of 360 mg/day prn. Or 180-240 mg (extended-release) PO once qd. Adjust based on pt response to max of 480 mg qd.
Atrial fibrillation or flutter; paroxysmal SVT
Adolescent, adult: 0.25 mg/kg IV bolus over 2 min. Repeat after 15 min if response inadequate with 0.35 mg/kg IV over 2 min. Follow bolus with continue IV infusion at 5-15 mg/h for up to 24 h. |